This idea had been out of fashion for decades, in part due to research in the 1880s by August Weismann.
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This opinion was challenged in the late 1970s by the Australian doctors Robin Warren and Barry Marshall, who suspected that stomach problems were caused by infection with the bacteria Helicobacter pylori.
They originated about 245 Ma, during the recovery from the Permian-Triassic mass extinction, and then remained insignificant until they exploded in diversity and ecological importance during the Late Triassic.
Henceforth the tendency to silence scientists with inconvenient opinions has been labeled Lysenkoism since it provides the most famous example of the harm that can be done when competing scientific opinions cannot be expressed equally freely.
It's random and the randomness is done every time you issue a command, so sitting doing nothing would not activate it.